000			02018 am a22002413u 4500
042			_adc
100	1	0	_aJamison, Andrea L. _eauthor _9729
700	1	0	_aSlightam, Cindie _eauthor _9730
700	1	0	_aBertram, Franziska _eauthor _9731
700	1	0	_aKim, Sunyoung _eauthor _9732
700	1	0	_aRoth, Walton T. _eauthor _9733
245	0	0	_aRandomized Clinical Trial of Capnometry-Assisted Respiratory Training in Veterans with Posttraumatic Stress Disorder Hyperarousal
260			_c2022-07.
500			_a/pmc/articles/PMC7272253/
500			_a/pubmed/31804108
520			_aOBJECTIVE: To investigate if capnometry-assisted anti-hyperventilation respiratory training, successful in treating panic, and sleep hygiene instructions would reduce posttraumatic stress disorder (PTSD) hyperarousal symptoms in U.S. military veterans. METHOD: We conducted a parallel, non-blinded clinical trial and randomized 80 veterans with PTSD hyperarousal into treatment or waitlist. Primary treatment outcomes from baseline to first follow-up were analyzed using mixed modeling. Baseline physiological measures were compared between the PTSD hyperarousal group and a no-PTSD group (n = 68). RESULTS: Baseline respiration rate but not partial-pressure of end-tidal carbon dioxide (PCO(2)) were higher in the PTSD hyperarousal group than the no-PTSD group during three minutes of quiet sitting, indicating no difference in baseline hyperventilation. There was no significant effect of the intervention on PTSD hyperarousal symptoms or hyperventilation compared to waitlist, but treatment did lower respiratory rate. CONCLUSION: This intervention did not reduce PTSD hyperarousal symptoms, perhaps due to differences between underlying mechanisms of PTSD hyperarousal and panic disorder or to differences between veteran and civilian populations.
540			_a
546			_aen
690			_aArticle
655	7		_aText _2local
786	0		_nPsychol Trauma
856	4	1	_uhttp://dx.doi.org/10.1037/tra0000525 _zConnect to this object online.
999			_c691 _d691