000 02426 am a22002893u 4500
042 _adc
100 1 0 _aMatthew, Jacqueline
_eauthor
_91889
700 1 0 _aSkelton, Emily
_eauthor
700 1 0 _aStory, Lisa
_eauthor
700 1 0 _aDavidson, Alice
_eauthor
_92575
700 1 0 _aKnight, Caroline L.
_eauthor
700 1 0 _aGupta, Chandni
_eauthor
_92577
700 1 0 _aPasupathy, Dharmintra
_eauthor
_92578
700 1 0 _aRutherford, Mary
_eauthor
245 0 0 _aMRI-Derived Fetal Weight Estimation in the Midpregnancy Fetus: A Method Comparison Study
260 _c2021-01-01.
500 _a/pmc/articles/PMC7614116/
500 _a/pubmed/34818233
520 _aOBJECTIVES: The aim of this study was to compare the standard ultrasound (US) estimated fetal weight (EFW) and MRI volume-derived methods for the midtrimester fetus. METHODS: Twenty-five paired US and MRI scans had the EFW calculated (gestational age [GA] range = 20-26 weeks). The intra- and interobserver variability of each method was assessed (2 operators/modality). A small sub-analysis was performed on 5 fetuses who were delivered preterm (mean GA 29 (+3) weeks) and compared to the actual birthweight. RESULTS: Two MRI volumetry EFW formulae under-measured compared to US by −10.9% and −14.5% in the midpregnancy fetus (p < 0.001) but had excellent intra- and interobserver agreement (intraclass correlation coefficient = 0.998 and 0.993). In the preterm fetus, the mean relative difference (MRD) between the MRI volume-derived EFW (MRI-EFW) and actual expected birthweight (at the scan GA) was −13.7% (−159.0 g, 95% CI: −341.7 to 23.7 g) and −17.1% (−204.6 g, 95% CI: −380.4 to −28.8 g), for the 2 MRI formulae. The MRD was smaller for US at 5.3% (69.8 g, 95% CI: −34.3 to 173.9). CONCLUSIONS: MRI-EFW results should be interpreted with caution in midpregnancy. Despite excellent observer agreement with MRI volumetry, refinement of the EFW formula is needed in the second trimester, for the small and for the GA and preterm fetus to compensate for lower fetal densities.
540 _a
540 _ahttps://creativecommons.org/licenses/by/4.0/This work is licensed under a CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/) International license.
546 _aen
690 _aArticle
655 7 _aText
_2local
786 0 _nFetal Diagn Ther
856 4 1 _uhttp://dx.doi.org/10.1159/000519115
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999 _c2185
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