000 02215 am a22002413u 4500
042 _adc
100 1 0 _aDaines, Luke
_eauthor
_91050
700 1 0 _aZheng, Bang
_eauthor
_91051
700 1 0 _aPfeffer, Paul
_eauthor
_91052
700 1 0 _aHurst, John R
_eauthor
_91053
700 1 0 _aSheikh, Aziz
_eauthor
_91054
245 0 0 _aA clinical review of long-COVID with a focus on the respiratory system
260 _c2022-05-01.
500 _a/pmc/articles/PMC7612723/
500 _a/pubmed/35131989
520 _aPURPOSE OF REVIEW: Persistence of symptoms after acute COVID-19, often described as long-COVID, is common and debilitating. In this article, we review the epidemiology, clinical features, and research priorities for long-COVID focusing on the respiratory system. RECENT FINDINGS: Breathlessness, cough and chest pain were the most commonly reported respiratory symptoms associated with long-COVID. In hospitalised patients, abnormalities on lung function testing or chest imaging were observed less commonly at 12 months compared to six months since discharge. Clinical assessment of patients with persisting symptoms after acute COVID-19 requires a comprehensive evaluation to exclude other possible causes for symptoms. With no robust current evidence for interventions to treat long-COVID respiratory symptoms, symptomatic treatment, supported self-management and pulmonary rehabilitation should be considered to help individuals with respiratory symptoms associated with long-COVID. SUMMARY: Long-COVID is a debilitating syndrome which often includes persisting respiratory symptoms and to a lesser degree, abnormalities in lung physiology or imaging. Respiratory features of long-COVID may reduce over time, yet resolution is not seen in all cases. Future research is needed to understand the natural history of long-COVID, identify factors associated with spontaneous improvement/persistence, investigate mechanisms for persisting symptoms, and test interventions to prevent and treat long-COVID.
540 _a
546 _aen
690 _aArticle
655 7 _aText
_2local
786 0 _nCurr Opin Pulm Med
856 4 1 _uhttp://dx.doi.org/10.1097/MCP.0000000000000863
_zConnect to this object online.
999 _c1711
_d1711