TY  - BOOK
AU  - Jamison,Andrea L.
AU  - Slightam,Cindie
AU  - Bertram,Franziska
AU  - Kim,Sunyoung
AU  - Roth,Walton T.
TI  - Randomized Clinical Trial of Capnometry-Assisted Respiratory Training in Veterans with Posttraumatic Stress Disorder Hyperarousal
PY  - 2022///-07
KW  - Text
KW  - local
N1  - /pmc/articles/PMC7272253; /pubmed/31804108
N2  - OBJECTIVE: To investigate if capnometry-assisted anti-hyperventilation respiratory training, successful in treating panic, and sleep hygiene instructions would reduce posttraumatic stress disorder (PTSD) hyperarousal symptoms in U.S. military veterans. METHOD: We conducted a parallel, non-blinded clinical trial and randomized 80 veterans with PTSD hyperarousal into treatment or waitlist. Primary treatment outcomes from baseline to first follow-up were analyzed using mixed modeling. Baseline physiological measures were compared between the PTSD hyperarousal group and a no-PTSD group (n = 68). RESULTS: Baseline respiration rate but not partial-pressure of end-tidal carbon dioxide (PCO(2)) were higher in the PTSD hyperarousal group than the no-PTSD group during three minutes of quiet sitting, indicating no difference in baseline hyperventilation. There was no significant effect of the intervention on PTSD hyperarousal symptoms or hyperventilation compared to waitlist, but treatment did lower respiratory rate. CONCLUSION: This intervention did not reduce PTSD hyperarousal symptoms, perhaps due to differences between underlying mechanisms of PTSD hyperarousal and panic disorder or to differences between veteran and civilian populations
UR  - http://dx.doi.org/10.1037/tra0000525
ER  -