The Development and Internal Evaluation of a Predictive Model to Identify for Whom Mindfulness-Based Cognitive Therapy Offers Superior Relapse Prevention for Recurrent Depression Versus Maintenance Antidepressant Medication (Record no. 2294)
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042 ## - AUTHENTICATION CODE | |
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Authentication code | dc |
100 10 - MAIN ENTRY--PERSONAL NAME | |
Personal name | Cohen, Zachary D. |
Relator term | author |
9 (RLIN) | 2496 |
245 00 - TITLE STATEMENT | |
Title | The Development and Internal Evaluation of a Predictive Model to Identify for Whom Mindfulness-Based Cognitive Therapy Offers Superior Relapse Prevention for Recurrent Depression Versus Maintenance Antidepressant Medication |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Name of publisher, distributor, etc. | SAGE Publications, |
Date of publication, distribution, etc. | 2022-04-29. |
500 ## - GENERAL NOTE | |
General note | /pmc/articles/PMC7614103/ |
500 ## - GENERAL NOTE | |
General note | /pubmed/36698442 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Depression is highly recurrent, even following successful pharmacological and/or psychological intervention. We aimed to develop clinical prediction models to inform adults with recurrent depression choosing between antidepressant medication (ADM) maintenance or switching to mindfulness-based cognitive therapy (MBCT). Using previously published data (N = 424), we constructed prognostic models using elastic-net regression that combined demographic, clinical, and psychological factors to predict relapse at 24 months under ADM or MBCT. Only the ADM model (discrimination performance: area under the curve [AUC] = .68) predicted relapse better than baseline depression severity (AUC = .54; one-tailed DeLong's test: z = 2.8, p = .003). Individuals with the poorest ADM prognoses who switched to MBCT had better outcomes compared with individuals who maintained ADM (48% vs. 70% relapse, respectively; superior survival times, z = −2.7, p = .008). For individuals with moderate to good ADM prognoses, both treatments resulted in similar likelihood of relapse. If replicated, the results suggest that predictive modeling can inform clinical decision-making around relapse prevention in recurrent depression. |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
Terms governing use and reproduction | © The Author(s) 2022 |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
Terms governing use and reproduction | https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
546 ## - LANGUAGE NOTE | |
Language note | en |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | Empirical Articles |
9 (RLIN) | 2505 |
655 7# - INDEX TERM--GENRE/FORM | |
Genre/form data or focus term | Text |
Source of term | local |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | DeRubeis, Robert J. |
Relator term | author |
9 (RLIN) | 2497 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hayes, Rachel |
Relator term | author |
9 (RLIN) | 2498 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Watkins, Edward R. |
Relator term | author |
9 (RLIN) | 2499 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Lewis, Glyn |
Relator term | author |
9 (RLIN) | 2500 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Byng, Richard |
Relator term | author |
9 (RLIN) | 2501 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Byford, Sarah |
Relator term | author |
9 (RLIN) | 2502 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Crane, Catherine |
Relator term | author |
9 (RLIN) | 2503 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kuyken, Willem |
Relator term | author |
9 (RLIN) | 2504 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Dalgleish, Tim |
Relator term | author |
9 (RLIN) | 1970 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Schweizer, Susanne |
Relator term | author |
9 (RLIN) | 1969 |
786 0# - DATA SOURCE ENTRY | |
Note | Clin Psychol Sci |
856 41 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://dx.doi.org/10.1177/21677026221076832">http://dx.doi.org/10.1177/21677026221076832</a> |
Public note | Connect to this object online. |
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