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MRI-Derived Fetal Weight Estimation in the Midpregnancy Fetus: A Method Comparison Study (Record no. 2185)

MARC details
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Personal name Matthew, Jacqueline
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9 (RLIN) 1889
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Title MRI-Derived Fetal Weight Estimation in the Midpregnancy Fetus: A Method Comparison Study
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Date of publication, distribution, etc. 2021-01-01.
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General note /pmc/articles/PMC7614116/
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General note /pubmed/34818233
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Summary, etc. OBJECTIVES: The aim of this study was to compare the standard ultrasound (US) estimated fetal weight (EFW) and MRI volume-derived methods for the midtrimester fetus. METHODS: Twenty-five paired US and MRI scans had the EFW calculated (gestational age [GA] range = 20-26 weeks). The intra- and interobserver variability of each method was assessed (2 operators/modality). A small sub-analysis was performed on 5 fetuses who were delivered preterm (mean GA 29 (+3) weeks) and compared to the actual birthweight. RESULTS: Two MRI volumetry EFW formulae under-measured compared to US by −10.9% and −14.5% in the midpregnancy fetus (p < 0.001) but had excellent intra- and interobserver agreement (intraclass correlation coefficient = 0.998 and 0.993). In the preterm fetus, the mean relative difference (MRD) between the MRI volume-derived EFW (MRI-EFW) and actual expected birthweight (at the scan GA) was −13.7% (−159.0 g, 95% CI: −341.7 to 23.7 g) and −17.1% (−204.6 g, 95% CI: −380.4 to −28.8 g), for the 2 MRI formulae. The MRD was smaller for US at 5.3% (69.8 g, 95% CI: −34.3 to 173.9). CONCLUSIONS: MRI-EFW results should be interpreted with caution in midpregnancy. Despite excellent observer agreement with MRI volumetry, refinement of the EFW formula is needed in the second trimester, for the small and for the GA and preterm fetus to compensate for lower fetal densities.
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Terms governing use and reproduction
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Terms governing use and reproduction https://creativecommons.org/licenses/by/4.0/This work is licensed under a CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/) International license.
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Language note en
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Topical term or geographic name as entry element Article
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Genre/form data or focus term Text
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Personal name Skelton, Emily
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Personal name Story, Lisa
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Personal name Davidson, Alice
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9 (RLIN) 2575
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Personal name Knight, Caroline L.
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Personal name Gupta, Chandni
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9 (RLIN) 2577
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Personal name Pasupathy, Dharmintra
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9 (RLIN) 2578
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Personal name Rutherford, Mary
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Note Fetal Diagn Ther
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Uniform Resource Identifier <a href="http://dx.doi.org/10.1159/000519115">http://dx.doi.org/10.1159/000519115</a>
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