JOM KITA KE POLITEKNIK

Low utilization of direct-acting antiviral agents in a large national cohort of HIV and HCV co-infected Medicare patients in the United States: Implications for HCV elimination (Record no. 217)

MARC details
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Personal name Du, Ping
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9 (RLIN) 796
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Title Low utilization of direct-acting antiviral agents in a large national cohort of HIV and HCV co-infected Medicare patients in the United States: Implications for HCV elimination
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Date of publication, distribution, etc. 2022.
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General note /pmc/articles/PMC7391052/
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General note /pubmed/32011599
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Summary, etc. HCV infection is common in people living with HIV/AIDS (PLWHA). The advent of direct-acting antiviral agents (DAAs) has made HCV elimination a realistic goal. We conducted a retrospective cohort study using the U.S. Medicare Fee-For-Service claims data and outpatient prescription drug data to assess the HCV DAA initiation and completion among newly diagnosed HIV-HCV co-infected Medicare patients enrolled in 2014-2016. DAA initiation was defined as filling at least one prescription of DAAs during 2014-2016. DAA completion was defined as taking an 8-week or longer DAA treatment course for patients without cirrhosis and a 12-week or longer treatment duration for those with cirrhosis. Among 12,152 HIV-HCV co-infected Medicare patients, 20.9% received the DAA treatment in 2014-2016. The average time from HCV diagnosis to DAA initiation was 277 days. The overall DAA completion rate was 92% among 2,537 patients who used DAAs. Interventions are needed to improve DAA uptake in PLWHA.
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Language note en
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Topical term or geographic name as entry element Article
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Personal name Jung, Jeah
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9 (RLIN) 797
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Personal name Kalidindi, Yamini
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9 (RLIN) 798
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Personal name Farrow, Kevin
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9 (RLIN) 799
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Personal name Riley, Thomas
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9 (RLIN) 800
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Personal name Whitener, Cynthia
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9 (RLIN) 801
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Note J Public Health Manag Pract
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Uniform Resource Identifier <a href="http://dx.doi.org/10.1097/PHH.0000000000001147">http://dx.doi.org/10.1097/PHH.0000000000001147</a>
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